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Paratuberculosis
Diagnosis of subclinical infection is very difficult an therefore, vaccination remains as a key tool for effective control of Paratuberculosis.
Affected species



Contamination
TRANSMISSION
Oral transmission
Contaminated Food, soil, water,
milk and colostrum.
Transplacental transmission
In almost 40% of cows with subclinical disease.
RISK FACTORS
- Replacement of animals from herds with unknown paratuberculosis status
- Contact of young replacers with adult animal faeces
- Water and food contamination
- Contamination of calves by faeces in udders
- Poor equipement hygiene
ECONOMIC LOSSES
Livestock production
CLINICAL SIGNS
Diarrhea and progressive weight loss
General weakness
Decrease of production
STAGES OF DISEASE
1 ANIMAL IN STAGE 4, INDICATES 24 ANIMALS
WITH THE PROLIFERATION OF THE DISEASE
DR. RAMÓN A. JUSTE
Researcher at NEIKER
Dr. Ramón A. Juste got his Veterinary Medicine degree at the University of Zaragoza in 1979 and his PhD at the same university in 1990. After a period in clinical practice, he started his research career at the Basque Country research institute NEIKER (then SIMA), where he is still working after 4 years as Managing Director in SERIDA as Managing Director between 2015 and 2020. He participated in the first descriptions of several diseases not yet formally reported in Spain (bovine paratuberculosis, besnoitiosis, hereditary parakeratosis in calves, Oslerus rostratus in cats, etc.) and helped setting up a veterinary diagnostic service that later become the model for other in Spain. He has published over 200 scientific papers and has an h-index of 40 according to the WOS.

GUDAIR
Gudair is the only existing vaccine worldwide for the immunization of Mycobacterium avium ssp. paratuberculosis in sheep and goats

SILIRIUM
Silirum is an inactivated vaccine for the immunization of Mycobacterium avium ssp. paratuberculosis in cattle.